CUSTOM ITEM: HPLC Column, RP PFP, 5um, 4.0mm ID x 50mm Length, 100A. Cogent Brand. 1 EA.
Additional Info:
68522-05P-4 Cogent RP PFP™ HPLC Column has been a premium value trusted by HPLC laboratories for many years, delivering consistent performance and enhanced selectivity for challenging separations. This column is fully double end‑capped and bonded via a four‑carbon linker to a benzene ring substituted with five fluorine atoms, using ultra‑high purity silica.
The column enables multiple retention mechanisms—including π‑π interactions, dipole interactions, and hydrogen bonding—making it especially effective for halogenated, aromatic, and polar analytes. It is also suitable as an alternate column for USP methods requiring L43 classification.
With a 5 µm particle size, this column provides lower backpressure compared to smaller particle columns, allowing higher flow rates and robust performance while maintaining strong chromatographic efficiency.
50 mm Length – Fast Screening and Rapid Analysis
The 50 mm length is optimized for high‑speed separations and high‑throughput workflows.
Fast run times for screening applications
Reduced solvent consumption
Ideal for rapid method development and optimization
✅ Recommended for fast analytical workflows and screening applications
Flow Rate & System Requirements (4.0 mm ID, 5 µm)
⚠️ Compatible with standard analytical HPLC systems with low to moderate backpressure
Typical flow rate range: ~0.8 – 1.5 mL/min
Lower backpressure than 3 µm columns
Supports higher flow rates for faster analysis
Compatible with UV and standard detectors
✅ Best Practice: Filter samples using a 0.2 µm syringe filter prior to injection
Why Choose PFP (F5) Columns for Selective Separations
Enhanced Retention for Halogenated Compounds
Strong interaction with fluorinated and halogenated analytes
Improved selectivity vs C18 columns
Multiple Interaction Mechanisms
π‑π interactions for aromatic compounds
Dipole and hydrogen bonding interactions
Greater flexibility for method development
100 Å Pore Structure
Suitable for small to moderately sized molecules
Broader applicability compared to 60 Å columns
Cogent RP PFP™ Column Advantages
Fully End‑Capped Surface
Minimizes silanol activity
Improves peak symmetry
Robust Performance (5 µm Particles)
Lower backpressure vs smaller particle sizes
Reliable and consistent operation
High Purity Silica
Reproducible chromatographic results
Long column lifetime
Typical Applications
Halogenated compound screening
Aromatic compound separations
Rapid analytical workflows
Method development and optimization
USP L43 methods
Important Usage Notes
Packed and shipped in reversed‑phase solvents
Designed for standard analytical HPLC systems (4.0 mm ID)
Lower backpressure compared to smaller particle sizes
Use 0.2 µm filtration prior to injection
Made‑to‑Order Columns & Pricing Information
This is a custom, made‑to‑order column.
Columns are manufactured specifically to order
Orders cannot be canceled once placed
Custom columns are non‑returnable